Saturday, October 11, 2014

HPLC Solutions #122

How to Measure Noise (Part 1)
By John Dolan
This installment of HPLC Solutions begins a series on different measurements that we make on chromatograms. Measuring the baseline noise generated by an HPLC system may seem like a singularly boring subject. But if you think about it, noise can be a critical factor in the results of our analytical work. It is directly related to the limit of detection and limit of quantification, it can be used to determine the health of the detector, noise is a great diagnostic tool for problems, and can be a limiting factor in the precision of a method.

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Ref. & Thanks: Separation Science 

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